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Xcelience Expands Dry Granulation Capabilities

By Pharmaceutical Processing | September 28, 2010

Xcelience, a contract research organization, has expanded its solid oral dosage
form development and manufacturing capabilities to include a Vector
TFC-220 Roller Compactor in the GMP Manufacturing area. The addition of
this new equipment enables clients to achieve a faster transition from
development in the experimental area to GMP production of clinical
supplies.

Dry granulation technology represents an important option for
clients faced with development challenges resulting from moisture
sensitive active pharmaceutical ingredients (APIs).
Xcelience
currently maintains a Vector TFC-Lab Micro Roller Compactor in the
experimental area. The TFC-220 is a natural transition for scale-up to
the GMP Manufacturing area and significantly expands our processing
capacity for dry granulation. The TFC-220 is capable of processing
blends at a rate of up to 20 kg/hour.

“Taking a cross-functional approach to dry granulation ensures
effective technical transfer and supports improved manufacturing
outcomes,” says Ted Koontz, Director of Operations.

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