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Timing of COVID-19 vaccine doses sparks debate  

By Brian Buntz | January 4, 2021

The U.K. has delayed the second dose of COVID-19 vaccines to maximize the number of people who can receive the first vaccine dose.  

The move to delay administering the second dose by up to 12 weeks has prompted criticism from some physicians. The British Medical Association criticized the delay as “grossly unfair.”

Dr. Anthony Fauci recently said he disagreed with the strategy in a CNN interview. The U.S. would administer the second dose of the vaccine from Pfizer (NYSE:PFE) and BioNTech (NSDQ:BNTX) three weeks after the first, as the developers have recommended. 

Pfizer warned in a statement that “there is no data to demonstrate that protection after the first dose is sustained after 21 days.”

Spain’s health minister Salvador Illa echoed that sentiment in a recent press briefing today, stating the country would stick by its plan to administer the second Pfizer-BioNTech vaccine dose 21 days after the first.

Germany and Denmark, however, are considering following in the U.K.’s footsteps. 

The efficacy of the first dose of Pfizer-BioNTech vaccine is roughly 50%, said Dr. William C. Gruber, senior vice president of Pfizer Vaccine Clinical Research and Development. The efficacy rises to 95% following the second dose. 

About The Author

Brian Buntz

The pharma and biotech editor of WTWH Media, Brian is a veteran journalist with more than 15 years of experience covering an array of life science topics, including clinical trials, drug discovery and development and medical devices. Before coming to WTWH, he served as content director focused on connected devices at Informa. In addition, Brian covered the medical device sector for 10 years at UBM. At Qmed, he overhauled the brand’s news coverage and helped to grow the site’s traffic volume dramatically. He had previously held managing editor roles on two of the company’s medical device technology publications. Connect with him on LinkedIn or email at [email protected].

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