Polysep II media offers a triple layer design to improve process efficiency and extend the life of expensive final filters. Offering high retention, flow rate and throughput, the new membrane configuration provides a reliable prefiltration solution for sterilizing-grade membranes in aqueous-based applications. Comprised of borosilicate glass media and two cellulosic membranes, the integrated 1.0(m/0.2(m/0.1(m media combines the dirt-holding capacity of a depth filter with the retention efficiency of a membrane filter. The combination offers an unsurpassed prefiltration solution for cell culture and other media filtration applications. In addition, the new Polysep II triple layer media is ideal for designing scalable solutions from bench top to full-scale manufacturing.