The SciPure TFF System automates, optimizes and documents protein concentration and protein washing applications. SciPure’s patented technology includes on-board software and hardware providing constant TMP and constant flow rate – regardless of retentate viscosity changes. Provides continuous monitoring, control and documentation of trans-membrane pressure (TMP), inlet pressure (P1), retentate line pressure (P2), permeate line pressure (P3). SciPure displays and puts into spreadsheet/graphs 15 filtration-related parameters providing instantaneous overview of the filtration progress and status. Unit eliminates operator monitoring, eliminates operator adjustment, eliminates operator manual documentation, regardless of retentate viscosity changes. Six, user-definable alarms make for a walk-away, self-supervisory liquid handling system.