Bubble elimination in a prefilled syringe offers many advantages for drug developers when deciding how a product is to be packaged for clinical studies or commercial distribution. In a number of studies, Hyaluron Contract Manufacturing, found that the advantages of prefilled syringes can be further enhanced by reducing the size of the air (gas) bubble inside the syringe or better yet, eliminating it totally. After tests and validated studies a new and innovative method has been developed to fill syringes that will eliminate the air bubble. Patented and trademarked, BUBBLE-FREE FILLING® is now available. Prefilled syringes instead of vials have become the container of choice for parenteral drug delivery. The technique of BUBBLE-FREE FILLING further enhances the benefits of prefilled syringes. The key advantages of prefilled syringes are: safety in administration, ease of use (for both healthcare professionals and end users), reduced risk of contamination, less waste of costly or scarce API, improved dosing accuracy, and improved sterility assurance.
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