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Quick Change Sparger System Reduces Replacement Tasks

By Pharmaceutical Processing | March 26, 2010

Quick Change Sparger reduces the time and effort to replace the porous metal sparger elements found in bioreactor and fermentor tanks. After each batch, a new tip can be installed on the end of the assembly and is ready for steam in place operation. Or the sparger tip can be cleaned out of place utilizing a number of methods including ultrasonic cleaning or detergent and water flush. Changing to new clean sparger tips after each batch provides an excellent method of maintaining GMP process validation methods while reducing the time and cost between batch process. Using a porous metal sparger greatly increases mass transfer rates in bioreactors and fermentors. The introduction of gases into stirred or unstirred reactor vessels via millions of tiny bubbles increases the gas-to-liquid contact areas allowing for optimal mass transfer rates. In-tank applications, with sparging elements located inside the tank, can be batch or continuous flow, with or without agitation.

Mott Corporation, Farmington, CT 06032. www.mottcorp.com or call 800-289-6688

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