Pharmaceutical Processing World

  • Home
  • Regulatory
    • Recalls
  • Pharmaceutical Processing
  • Facility
  • Supply Chain
  • Equipment and Materials
  • Contract Manufacturing
  • R&D 100 Awards

Pfizer’s Paxlovid holds up to omicron in studies

By Brian Buntz | January 19, 2022

Pfizer logoPfizer (NYSE:PFE) revealed that its COVID-19 drug Paxlovid retained in vitro efficacy against the omicron SARS-CoV-2 variant.

The company said that the research indicates that the drug can potentially maintain plasma concentrates “many-fold” times higher than the level needed to prevent replication of the highly transmissible variant.

“These data suggest that our oral COVID-19 therapy can be an important and effective tool in our continued battle against this devastating virus and current variants of concern,” said Dr. Mikael Dolsten, chief scientific officer at Pfizer, in a statement.

Demand for Paxlovid, which FDA authorized in late December, has far exceeded supply.

In January, the White House announced that the federal government would buy 20 million courses of Paxlovid — twice as much as initially planned.

Paxlovid combines two antivirals — nirmatrelvir and ritonavir.

In November 2021, Pfizer also announced a license agreement with the Medicines Patent Pool to authorize the distribution of Paxlovid to close to 100 countries.

A recent feature in Chemical & Engineering News noted that Paxlovid went from initial idea to first clinical trial within 12 months.

In December 2021, the company revealed that the drug reduced hospitalization or death by 89% when administered within three days of symptom onset in a Phase 2/3 study. Administering the antiviral cocktail within five days of symptom onset was 88% efficacious.

Early data from Israel suggests that more than 90% of people infected with COVID-19 improve, according to The Jerusalem Post.

Tell Us What You Think! Cancel reply

Related Articles Read More >

vaccine
Will COVID-19 vaccines be updated by fall? 
COVID-19 vaccine
Young children in U.S. now eligible for COVID-19 vaccination
Florida
Florida chooses to not pre-order COVID-19 vaccines for young children
Pfizer logo
Pfizer to spend $120M to make COVID-19 oral treatment in U.S.

DeviceTalks Tuesdays

DeviceTalks Tuesdays

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.

Need Pharmaceutical Processing news in a minute?

We Deliver!
Pharmaceutical Processing Enewsletters get you caught up on all the mission critical news you need. Sign up today.
Enews Signup
Pharmaceutical Processing World
  • Subscribe to Our Free E-Newsletter
  • Contact Us
  • About Us
  • Advertise With Us
  • R&D World
  • Drug Delivery Business News
  • Drug Discovery & Development
  • DeviceTalks
  • MassDevice
  • Medical Design & Outsourcing
  • MEDICAL TUBING + EXTRUSION
  • Medical Design Sourcing
  • Medtech100 Index

Copyright © 2022 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search Pharmaceutical Processing World

  • Home
  • Regulatory
    • Recalls
  • Pharmaceutical Processing
  • Facility
  • Supply Chain
  • Equipment and Materials
  • Contract Manufacturing
  • R&D 100 Awards