Novartis (NYSE:NVS) has inked a deal with the biopharma Carisma Therapeutics focused on the production of human epidermal growth factor receptor 2 (HER2)-targeted chimeric antigen receptor macrophages (CAR-M) to potentially treat solid tumors.

Carisma is headquartered in Philadelphia.

As part of the deal, Carisma will shift manufacturing to a Novartis cell therapy site in Morris Plains, New Jersey.

Novartis anticipates clinical manufacturing to begin in 2023.

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