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Molecular Templates Completes Merger with Threshold Pharmaceuticals and Private Placements

By GlobeNewswire | August 2, 2017

Molecular Templates, Inc., a clinical stage biopharmaceutical company focused on the discovery and development of Engineered Toxin Bodies (ETBs), a new class of targeted biologic therapies that possess unique mechanisms of action in oncology, announced the completion of its previously announced merger with Threshold Pharmaceuticals, Inc., effective as of August 1, 2017. 

Following the completion of the merger, Molecular Templates completed a previously announced $40.0 million equity financing led by venture capital firm Longitude Capital, which invested $20.0 million in the combined company, with an additional $20.0 million from CAM Capital, BVF, Perceptive Advisors and others, including certain affiliates of Molecular Templates. 

In addition, following the completion of the merger and the Longitude-led financing, the combined company closed a $20.0 million equity investment from Takeda Pharmaceutical Company Ltd. made in connection with Molecular Templates’ entry into a collaboration and license agreement with Takeda.   Together with pre-merger cash on Threshold’s balance sheet, and giving effect to the private placements, the combined company has a cash balance of approximately $75.0 million for use in funding its research and development activities.

The holders of shares of Molecular Templates common stock outstanding immediately prior to the merger received 7.7844 shares of Threshold common stock in exchange for each share of Molecular Templates common stock in the merger.  The exchange ratio reflects a 1-for-11 reverse stock split effected by Threshold prior to the completion of the merger.  Following the completion of the merger and the equity financings, the combined company has approximately 26,880,899 shares of common stock outstanding.

Following the completion of the merger, Threshold changed its name to Molecular Templates, Inc.  The combined company will commence trading on August 2, 2017 on The Nasdaq Capital Market under the ticker symbol “MTEM.”

“The completion of these transactions is an exciting step in the evolution of Molecular Templates as we enter the public markets,” said Eric Poma, Ph.D., President, Chief Executive Officer and Chief Scientific Officer of Molecular Templates.   “We are now well-funded and have the resources to further the development of our lead ETB product candidate, MT-3724, with new clinical efficacy and safety data from an MTD expansion study in relapsed/refractory DLBCL patients expected in 2018, and to develop our pipeline of drug candidates based on our next generation ETBs, the first of which is expected to enter the clinic in 2018.  We are also committed to exploring Threshold’s evofosfamide (formerly TH-302), which is currently in a Phase 1 clinical trial in combination with ipilimumab in advanced solid tumors.”

“I want to express my gratitude to the Threshold stockholders for supporting the merger with Molecular Templates, whose technology and clinical candidates we believe are differentiated with great promise for addressing significant unmet needs in the treatment of patients living with cancer,” said Harold (“Barry”) E. Selick, Ph.D., Threshold’s former Chief Executive Officer and chairman of the Board of Directors of the combined company.  “I am looking forward to supporting the success of the combined organization.”

Following the completion of the merger, Threshold moved its corporate headquarters to Austin, Texas. The combined company operates under the leadership of Molecular Templates’ management, including Eric E. Poma, Ph.D., as Chief Executive Officer and Chief Scientific Officer, and Jason Kim, President and Chief Operating Officer.  In addition to Dr. Selick continuing as chairman, the Board of Directors of the combined company will include Dr. Poma, Kevin M. Lalande of Santé Ventures, David Hirsch M.D, Ph.D. of Longitude Capital, Scott Morenstein of CAM Capital, David R. Hoffmann of DRH Consulting and Michael Broxson of Takeda Pharmaceuticals.

Threshold’s financial advisor for the transaction is Ladenburg Thalmann & Co. Inc., and Threshold’s legal counsel is Cooley LLP.  Molecular Templates’ legal counsel is Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.

(Source: Nasdaq)

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