Pharmaceutical Processing World

  • Home
  • Regulatory
    • Recalls
  • Pharmaceutical Processing
  • Facility
  • Supply Chain
  • Equipment and Materials
  • Contract Manufacturing
  • Resources
    • Voices
  • Advertise
  • SUBSCRIBE

Millipore and Microbix Form Strategic Partnership to Develop Novel Purification Process in Vaccine Manufacturing

By Pharmaceutical Processing | April 23, 2009

Millipore Corporation and Microbix Biosystems Inc ., have formed a scientific collaboration to develop a novel purification process for influenza virus vaccine manufacturing. As part of the collaboration, Millipore plans to develop a new technology for single step purification of influenza virus to replace ultracentrifugation. Influenza vaccine is currently produced in eggs and is purified using ultracentrifugation. Ultracentrifugation is an expensive and complex process that can create bottlenecks in process development during manufacturing scale-up. The single step purification process, based on novel chromatographic technology being developed by Millipore, has the potential to reduce the complexity and capital cost associated with current manufacturing processes. Microbix will supply egg-based influenza virus for use in product development studies. Microbix will also provide Millipore with access to its VirusmaxTM technology, a patented process that has been shown to significantly increase the recovery and purity of influenza virus produced in eggs. “Millipore remains focused on pioneering innovation for the biopharmaceutical industry. Developing new vaccine purification technologies that improve both the efficiency and economics of manufacturing is of paramount importance to us,” said Jean-Paul Mangeolle, President, Bioprocess Division, Millipore Corporation. “Microbix is very pleased to participate with Millipore in this scientific collaboration,” said William J. Gastle, Chief Executive Officer, Microbix. “Use of our unique Virusmax technology will ensure that maximal yields are realized in process development studies and provide greater flexibility in the choice of virus strains for influenza vaccine applications.” The market for influenza vaccines is estimated to be more than $2 Billion dollars today and threat of an expected pandemic is expected to double this market by 2016. This research will be conducted in Millipore’s Vaccine Process Research Laboratory in Bedford, MA. The lab focuses on new technologies for conventional vaccine manufacturing as well as new single-use processes.

Related Articles Read More >

Great Point Partners logo.
Great Point Partners acquires majority stake in Eutecma to fuel sustainable cold chain growth
Driving success in fast-paced high-tech pharma construction projects
This is a photo of the Fujifilm Diosynth Biotechnologies plant under construction in Holly Springs, North Carolina.
Fujifilm, Regeneron ink $3B U.S. manufacturing agreement
This is the logo of Johnson & Johnson.
J&J breaks ground on $2B manufacturing facility in North Carolina
“ppw
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest news, technologies, and developments in Pharmaceutical Processing.

DeviceTalks Tuesdays

DeviceTalks Tuesdays

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.
Pharmaceutical Processing World
  • Subscribe to our E-Newsletter
  • Contact Us
  • About Us
  • R&D World
  • Drug Delivery Business News
  • Drug Discovery & Development
  • DeviceTalks
  • MassDevice
  • Medical Design & Outsourcing
  • MEDICAL TUBING + EXTRUSION
  • Medical Design Sourcing
  • Medtech100 Index
  • R&D 100 Awards

Copyright © 2025 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search Pharmaceutical Processing World

  • Home
  • Regulatory
    • Recalls
  • Pharmaceutical Processing
  • Facility
  • Supply Chain
  • Equipment and Materials
  • Contract Manufacturing
  • Resources
    • Voices
  • Advertise
  • SUBSCRIBE