In sterile manufacturing areas, cGMP is a critical issue. Serial addresses this issue with a proven CIP/SIP system combined with an advantageous door closing system. The door system is both double-sealed and double-hinged to ensure a higher dependability and assure a higher level of compliance with cGMP. The CIP system employs rotating spray columns for 100% cleaning. SIP systems are complete with sterile filter, liquid pump for drying and full process control and validation.