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Emergent BioSolutions Expands Manufacturing Capability

By ABEC | September 25, 2018

ABEC, a global provider of integrated solutions and services for biopharmaceutical manufacturing, will provide CSR dual purpose single-use systems to Emergent BioSolutions for large scale 750L microbial fermentation and 500L mammalian cell culture. The dual purpose systems are custom designed to accommodate Emergent’s process needs and operational requirements and complement Emergent’s 4,000L CSR single-use bioreactor capability.

Integration of ABEC’s CSR dual purpose systems significantly advances Emergent’s commercial operations capabilities. Emergent can utilize the same equipment platform to provide multi-product, multi-platform and multi-scale manufacturing. This includes the ability to utilize the same CSR platform for microbial and cell culture. Changeover from microbial processing to mammalian and vice versa is accomplished simply by changing the Disposable Container (DC) used for these processes.

The systems also deliver process performance comparable to stainless steel systems, a key benefit of the CSR platform. In particular, Emergent is now able to achieve the vigorous mixing and high gassing rates required for state-of-the-art microbial fermentation in a large-scale single-use system.

“Emergent’s diverse customers require both mammalian and microbial processes to produce a wide variety of vaccines and therapeutics,” said Scott Battist, Emergent BioSolutions vice president and general manager of the Bayview site, “We are now able to quickly and cost-effectively provide manufacturing services utilizing either of these technologies.”

(Source: ABEC)

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