Pharmaceutical Processing World

  • Home
  • Regulatory
    • Recalls
  • Pharmaceutical Processing
  • Facility
  • Supply Chain
  • Equipment and Materials
  • Contract Manufacturing
  • Resources
    • Voices
  • Advertise
  • SUBSCRIBE

Eli Lilly invests more than $1.2B in Puerto Rico plant

By Sean Whooley | October 29, 2025

Eli Lilly Puerto Rico facility (1)

[Rendering courtesy of Eli Lilly]

Eli Lilly (NYSE:LLY) announced today that it plans to invest more than $1.2 billion to expand and modernize a manufacturing site in Puerto Rico.

The company plans to integrate advanced technologies and expand production capacity within the existing campus at its Lilly del Caribe plant in Carolina, Puerto Rico. It hopes to support its growing portfolio of oral solid medicines in cardiometabolic health, neuroscience, oncology and immunology.

Lilly said its facility’s capabilities include manufacturing orforglipron, its first oral, small-molecule GLP-1 receptor agonist. It plans to submit this to global regulatory agencies for obesity by the end of the year.

The company said its expansion underscores Puerto Rico’s role in its manufacturing agenda as part of a wider investment in U.S. manufacturing. Earlier this year, the company announced its plans to bolster domestic medicine production across therapeutic areas. That included the building of four new pharmaceutical sites in the U.S. Recent expansions include investments in Virginia and Texas.

Lilly said it plans for the facility to deploy highly advanced technologies in oral solid medicine manufacturing. That includes dock-to-dock automation and material flow, paperless manufacturing, process analytical technology and spray-dried dispersion.

The company expects to create up to 1,000 construction jobs and 100 additional high-tech manufacturing positions. It expects to begin construction in 2026, with plans to start producing medicine by the end of 2028.

“After sixty years, Lilly del Caribe continues to play an important role in making life-changing medicines for people in the U.S. and beyond,” said Edgardo Hernandez, EVP and president of Lilly Manufacturing Operations. “Our continued investments in capacity, infrastructure, advanced technologies and highly specialized jobs will further cement the site’s significance in Lilly’s global manufacturing network. Our progress builds on the dedication and expertise of our local team, helping us deliver new medicines for patients around the world.”

About The Author

Sean Whooley

Sean Whooley is an associate editor who mainly produces work for MassDevice, Medical Design & Outsourcing and Drug Delivery Business News. He received a bachelor's degree in multiplatform journalism from the University of Maryland, College Park. You can connect with him on LinkedIn or email him at swhooley@wtwhmedia.com.

Tell Us What You Think! Cancel reply

Related Articles Read More >

This is the logo of Novartis.
Novartis opens new manufacturing plant in California
Coriolis meter options for pharmaceutical applications
samsung biologics (1)
Samsung Biologics completes Bioepis spinoff to become pure-play pharma CDMO
Eli Lilly the Netherlands Facility (1)
Lilly plans new oral medicine manufacturing plant in Europe
“ppw
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest news, technologies, and developments in Pharmaceutical Processing.

DeviceTalks Tuesdays

DeviceTalks Tuesdays

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.
Pharmaceutical Processing World
  • Subscribe to our E-Newsletter
  • Contact Us
  • About Us
  • R&D World
  • Drug Delivery Business News
  • Drug Discovery & Development
  • DeviceTalks
  • MassDevice
  • Medical Design & Outsourcing
  • MEDICAL TUBING + EXTRUSION
  • Medical Design Sourcing
  • Medtech100 Index
  • R&D 100 Awards

Copyright © 2025 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search Pharmaceutical Processing World

  • Home
  • Regulatory
    • Recalls
  • Pharmaceutical Processing
  • Facility
  • Supply Chain
  • Equipment and Materials
  • Contract Manufacturing
  • Resources
    • Voices
  • Advertise
  • SUBSCRIBE