Pharmaceutical Processing World

  • Home
  • Regulatory
    • Recalls
  • Pharmaceutical Processing
  • Facility
  • Supply Chain
  • Equipment and Materials
  • Contract Manufacturing
  • R&D 100 Awards

Digoxin offers similar performance to the bisoprolol for AF patients with heart failure

By Brian Buntz | December 24, 2020

digon molecule

Ball-and-stick model of digon molecule from Wikipedia

A randomized trial published in JAMA concluded that there was no statistically significant difference in patient-reported quality of life for atrial-fibrillation (AF) patients with heart failure symptoms who took digoxin versus the beta-blocker bisoprolol (Zebeta). 

Digoxin was once widely used for heart failure but has become less popular after a 2015 study found patients who took the drug had a higher risk of death.  

But the recent JAMA study found while digoxin and bisoprolol offered similar performance after six months of therapy, digoxin patients fared better at 12 months. Patients who received digoxin not only had fewer adverse events, they fared better in eight out of 20 secondary outcomes in the study. 

Digoxin is available as a generic and under the brand name Lanoxin from Covis Pharma. Covis acquired rights to the drug from GlaxoSmithKline  (LON: GSK) in 2011. 

Zebeta is also offered as a generic and brand-name drug from Teva Pharmaceuticals (NYSE:TEVA).

Tell Us What You Think! Cancel reply

Related Articles Read More >

Novartis logo
Novartis mulls sale of $25 billion Sandoz generics arm
Pfizer logo
Pfizer seeks to comply with voluntary Net-Zero Standard by 2040
Fujifilm Diosynth Technologies
Fujifilm to spend $1.6B to bolster cell culture manufacturing services
Zantac
First Zantac trial slated for February 2023

DeviceTalks Tuesdays

DeviceTalks Tuesdays

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.

Need Pharmaceutical Processing news in a minute?

We Deliver!
Pharmaceutical Processing Enewsletters get you caught up on all the mission critical news you need. Sign up today.
Enews Signup
Pharmaceutical Processing World
  • Subscribe to Our Free E-Newsletter
  • Contact Us
  • About Us
  • Advertise With Us
  • R&D World
  • Drug Delivery Business News
  • Drug Discovery & Development
  • DeviceTalks
  • MassDevice
  • Medical Design & Outsourcing
  • MEDICAL TUBING + EXTRUSION
  • Medical Design Sourcing
  • Medtech100 Index

Copyright © 2022 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search Pharmaceutical Processing World

  • Home
  • Regulatory
    • Recalls
  • Pharmaceutical Processing
  • Facility
  • Supply Chain
  • Equipment and Materials
  • Contract Manufacturing
  • R&D 100 Awards