Biopharmaceutical reactor production unit incorporates the latest developments for the manufacture of vaccines, eyewash fluids, tablet coatings, adhesives, syrups, and other personal care products. These units range in size from 10- 2,500 gallon capacities, process low to high viscosity materials, powder and liquids, offer CIP or SIP cleaning options, and a bottom drive motor design for good hygienic processing conditions. Units can also be supplied with full controls, low-level detection, temperature monitoring, split top design for automated opening and closing, and other specialized or customized features such as dosing and metering raw materials into the vessel. Systems are built on skids to provide mobility and to accommodate modular manufacturing techniques.