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Aldevron and Ginkgo Bioworks announce mRNA manufacturing ‘breakthrough’

By Brian Buntz | August 10, 2021

Aldevron/GinkgoThe partnership between Aldevron (Fargo, N.D.) and Ginkgo Bioworks (Boston) has resulted in an improvement in the manufacturing yield of the vaccinia capping enzyme (VCE).

VCEs are often used in the production of mRNA vaccines and therapeutics.

The new production protocol is more than 10 times more efficient than the prior process, according to a statement from both firms. The gene therapy company Aldevron will have exclusive rights to the protocol conditions of the manufacturing process. Ginkgo Bioworks specializes in synthetic biology.

“Aldevron’s industry-leading products and services are the foundation for some of the most exciting advances in biological science today,” said Jason Kelly, CEO of Ginkgo Bioworks, in a statement.

Tom Foti, president of Aldevron’s protein business unit, predicted the new production method would “accelerate mRNA therapeutic and vaccine development for manufacturing teams around the world.”

Ginkgo Bioworks is poised to go public via a merger with Soaring Eagle Acquisition Company, a SPAC. Earlier this year, the investment firm Cathie Wood of Ark Invest pegged Ginkgo’s valuation at $15 billion.

Last month, Aldevron revealed a strategic partnership with AavantiBio focused on gene therapies for rare genetic diseases. Under the terms of the partnership deal, Aldevron will manufacture plasmids for AavantiBio’s gene therapy programs.

 

 

About The Author

Brian Buntz

The pharma and biotech editor of WTWH Media, Brian is a veteran journalist with more than 15 years of experience covering an array of life science topics, including clinical trials, drug discovery and development and medical devices. Before coming to WTWH, he served as content director focused on connected devices at Informa. In addition, Brian covered the medical device sector for 10 years at UBM. At Qmed, he overhauled the brand’s news coverage and helped to grow the site’s traffic volume dramatically. He had previously held managing editor roles on two of the company’s medical device technology publications. Connect with him on LinkedIn or email at bbuntz@wtwhmedia.com.

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